iCANX 69 期直播预告︱脑科学专家Nitish Thakor教授分享神经科学的前沿与挑战！

直播时间：9月17日（周五）20:00-21:30

直播地址：科学网新浪微博直播间https://weibo.com/l/wblive/p/show/1022:2321324682363811791837

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2021年9月17日晚 8:00（北京时间），大家期待已久的 iCANX Talks第69期即将重磅来袭，本期直播我们有幸邀请到约翰霍普金斯大学和新加坡国立大学的Nitish Thakor教授来到iCANX Talks讲座系列，敬请期待！

The highly expected iCANX Talks Vol.69 will be ceremoniously holed at 8:00 pm of September 17 (Beijing time). This time, we are fortunate to invite5 Professor Nitish Thakor from Johns Hopkins University and National University of Singaporeto the iCANX Talks lecture series. so stay tuned!

在前面68期iCANX Talks直播中，累计收看观众已经达到千万人次，受到了国内外专家学者的普遍好评和追捧，目前，iCANX Talks已经成为极具国际影响力的高科技云端学术峰会。

In the previous 68 weeks iCANX talks , it totally attracted close to 10 million audiences worldwide. iCANX has been highlighted by experts and audiences globally. Now, iCANX Talks already becomes a well-known and popular international high-tech online event.

话不多说，先让小艾给大家详细介绍重磅嘉宾及演讲内容吧！

Here comes the abstracts & Bios of today’s iCANX Talks!

报告介绍

Neuroengineering: Frontiers and Challenges

神经科学的前沿与挑战

Nitish Thakor

Johns Hopkins University and National University of Singapore

约翰霍普金斯大学和新加坡国立大学

Abstract

To ‘study brain’ we may benefit from technologies that can probe (record, interface, image, …) brain. I will focus on a selected few frontiers. Take a cue from Physicists’ study of universe, we need amazing technologies from atomic scale to galaxy and whole known universe scale. So, study of brain needs technologies that probe neurons at sub-cellular and cellular level and technologies that address or interface to the whole brain, its 80 billion neurons and their extensive networks. So, the first frontier of neurotechnology is probes for the nervous system. I will present frontiers and challenges of neural interfaces. Still, how do these neurons, regions of brain come together for a whole, how do you probe the function? That brings us to the second frontier of imaging the brain and studying brain’s ‘message’: neuronal and brain rhythms to study and encode neural activity and translate into rhythms that signal health, mental activity and even consciousness/death. I will present examples of brain rhythm analysis and how they can be deployed for basic research and clinical translation. So, if we can interface to brain and study brain’s message and clinical applications of monitoring brain in situations of life and death. Finally, I will end this talk with the emerging, popular and paradigm shifting field of brain machine interface. In one application of brain machine interface, from fundamental challenges of encoding of neuronal populations for application to neuroprosthesis. In another application of brain machine interface, there is need for noninvasive technologies, electrical, magnetic, optical or ultrasound. I will conclude with the challenge or ‘closing the loop’ to sense and control brain function in health and disease, BMI with sensory input, closed loop treatment of diseases such as epilepsy and Parkinson’s.

为了研究大脑，我们会使用各种技术（电记录，神经界面，成像等）对其探测，我主要专注于几种特定的前沿方向。以探索宇宙的方式为示例，物理学家们使用的惊人技术从原子尺度到银河系尺度再到整个已知宇宙尺度。而在研究大脑方面，也需要对神经细胞从亚细胞尺度到细胞尺度再到全脑尺度来进行探测，以此来理解脑内八百亿个神经元及其拓展出的网络。因此，神经工程的第一个前沿方向是神经界面，我将介绍当前神经界面的前沿与挑战。同时我们也需要了解众多神经元及不同脑区如何协同成为一个整体，我们应该如何探测它们。这将我们带到了研究大脑成像和大脑“信息”的第二个前沿领域：研究神经元和大脑的节律，这种节律如何编码神经活动，我们如何将这种节律与健康、心理活动、意识/死亡相解读。我将展示脑节律分析的例子，以及如何将它们翻译应用于基础研究和临床中。最后，我会以脑机接口这个当下新兴流行的范式转换领域来结束本次演讲。在脑机接口的其中一个应用中，基础挑战在于从编码神经元群到神经假体的应用。在脑机接口的另一个应用中，需要一系列诸如电、磁、光或超声波等的无创技术。我将以“闭环”脑机接口面临的挑战结束本次演讲，通过“闭环”来感知和调控大脑，一方面是具有感官输入的脑机接口，另一方面是癫痫和帕金森病等疾病的闭环治疗。

Biography

Nitish V. Thakor is a Professor of Biomedical Engineering, Electrical and Computer Engineering and at Johns Hopkins University since 1983. He also joined the National University of Singapore in 2012 and served as the Founding Director of Singapore Institute for Neurotechnology (SINAPSE). Prof. Thakor’s technical expertise is in the fields of Medical Instrumentation and Neuroengineering, where he has carried out research on many technologies for brain monitoring, implantable neurotechnologies, neuroprosthesis and brain-machine interface. He has published over 420 refereed journal papers (GH Index 85), obtained 16 US and international patents and co-founded 3 active companies. He was previously the Editor in Chief of IEEE Transactions on Neural Systems and Rehabilitation Engineering, and currently the EIC of Medical and Biological Engineering and Computing (Springer/Nature). He is the Editor of an upcoming authoritative reference Handbook of Neuroengineering. Prof. Thakor is a recipient of the Technical Achievement Award (Neuroengineering) as well as the Academic Career Award from the IEEE Engineering in Medicine and Biology Society. He received a Research Career Development Award from the National Institutes of Health and a Presidential Young Investigator Award from the National Science Foundation, and is a Fellow of the American Institute of Medical and Biological Engineering, Life Fellow of IEEE, Biomedical Engineering Society, and International Federation of Medical and Biological Engineering. He is a recipient of a Distinguished Alumnus Award from Indian Institute of Technology, Bombay, India, and a Centennial Medal from the University of Wisconsin School of Engineering. In 2021 he was elected to the US National Academy of Inventors.

Nitish V. Thakor自 1983 年起在约翰斯霍普金斯大学的生物医学工程、电气和计算机工程专业担任教授。他于 2012 年加入新加坡国立大学，并担任新加坡神经技术研究所 (SINAPSE) 的创始主任。Thakor 教授是医疗仪器和神经工程领域的专家，他在脑监测、植入式神经技术、神经假体和脑机接口方面开展了多项技术研究。他发表了 420 多篇参考期刊论文（GH 指数 85），获得了 16 项美国和国际专利，与他人共同创立了 3 家活跃公司。他是IEEE Transactions on Neural Systems and Rehabilitation Engineering曾任主编，也是EIC of Medical and Biological Engineering and Computing (Springer/Nature)的现任主编，参与编辑了即将出版的神经工程手册。Thakor 教授是 IEEE 医学和生物学工程学会颁发的技术成就奖（神经工程）和学术职业奖的获得者。他获得了美国国立卫生研究院的研究职业发展奖和美国国家科学基金会的总统青年研究员奖，美国医学和生物工程研究所的会士，IEEE生物医学工程学的终身会士，国际医学与生物工程联合会会士。他是印度孟买印度理工学院杰出校友奖和威斯康星大学工程学院百年纪念奖章的获得者。2021年他被选入美国国家发明家学会。

Keywords

Neuroengineering神经科学

Nervous system 神经界面

Neuronal 神经元

Brain machine interface 脑机接口

同时，本次讲座也邀请了来自爱荷华州立大学的Martin Thuo教授带来精彩的主持。来自卡内基梅隆大学的贺斌教授和北京大学的段小洁教授，天津大学的黄显教授担任嘉宾。以及来自北京大学的王浦鑫担任X挑战者。精彩不断，敬请期待！iCANX将继续努力，为科学交流服务，提供一个全球学术交流的顶级平台，敬请大家期待！

At the same time, this lecture also invited Professor Martin Thuo from Iowa State University to bring a wonderful host. Professor Bin He and Xiaojie Duan from Peking University， Professor Xian Huang from Tianjin University as guests. And Puxin Wang from Peking University as X-challenger. iCANX will continue to work hard to serve scientific exchanges and provide a top platform for global academic exchanges. Please look forward to it!