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| Biologics文献清单: 2025-2026年精选文章鉴读 |
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期刊名：Biologics
期刊主页：https://www.mdpi.com/journal/biologics
我们诚挚邀请您一同探索Biologics期刊精选的 2025–2026 年 10 篇高质量文章。本合集聚焦生物制剂与再生医学前沿，涵盖功能水凝胶与骨组织工程、胎儿治疗与新兴生物制剂、补体抑制剂相关感染风险、重度哮喘生物制剂临床缓解、全新蛋白质设计靶向致癌蛋白互作、斑秃细胞因子靶向治疗、紫苏叶提取物抗氧化与细胞应激、制药冻干与 QbD/AI 融合、细胞外基质生物支架免疫应答，以及间充质干细胞及衍生物在神经疾病再生医学中的应用。我们相信，这一合集将成为该领域研究者的重要资源。期刊所有文章均为开放获取，您可以免费且无限制地阅读全部出版内容。
1. Functional Hydrogels in Bone Tissue Engineering: From Material Design to Translational Applications
功能水凝胶在骨组织工程中的应用：从材料设计到转化应用
https://www.mdpi.com/2673-8449/6/1/2
Petraglia, F.M.; Giordano, S.; Santoro, A. Functional Hydrogels in Bone Tissue Engineering: From Material Design to Translational Applications.Biologics2026,6, 2.
2. The Evolving Landscape of Fetal Therapy: Surgical Interventions and Emerging Biologics
胎儿治疗领域的发展新态势：手术干预与新兴生物制剂
https://www.mdpi.com/2673-8449/6/2/11
Seker-Yilmaz, B.; Hill, M.; Baranello, G.; Loukogeorgakis, S.; Coppi, P.D.; Gissen, P.; Chitty, L.S. The Evolving Landscape of Fetal Therapy: Surgical Interventions and Emerging Biologics.Biologics2026,6, 11.
3 Complement Inhibitors and the Risk of (Breakthrough) Infections—Critical Analysis and Preventive Strategies
补体抑制剂与（突破性）感染风险——批判性分析与预防策略
https://www.mdpi.com/2673-8449/6/1/3
Halacova, N.; Brndiarova, M.; Slenker, B.; Ruzinak Bobcakova, A.; Schniederova, M.; Markocsy, A.; Urbancikova, I.; Jesenak, M. Complement Inhibitors and the Risk of (Breakthrough) Infections—Critical Analysis and Preventive Strategies.Biologics2026,6, 3.
4. Clinical Remission and Its Predictors After 12 Months of Biologic Therapy in Severe Asthma
重度哮喘患者接受生物制剂治疗12个月后的临床缓解及其预测因素
https://www.mdpi.com/2673-8449/6/1/4
Suzuki, T.; Tajiri, T.; Ozawa, Y.; Amakusa, Y.; Ito, K.; Mori, Y.; Fukumitsu, K.; Fukuda, S.; Kanemitsu, Y.; Uemura, T.; et al. Clinical Remission and Its Predictors After 12 Months of Biologic Therapy in Severe Asthma.Biologics2026,6, 4.
5. De Novo Protein Design Enables Targeting of Intractable Oncogenic Protein–Protein Interfaces
全新蛋白质设计使得能够靶向难治性致癌蛋白-蛋白相互作用界面
https://www.mdpi.com/2673-8449/6/1/9
Ram Prakash, V.; Najy, Y.; Garrett, K.; Edwards, B.F.P.; Kidder, B.L. De Novo Protein Design Enables Targeting of Intractable Oncogenic Protein–Protein Interfaces.Biologics2026,6, 9.
6. Cytokine-Targeting Biologic Therapies for Alopecia Areata: A Comprehensive Review of Mechanism of Action, Clinical Efficacy, and Adverse Events
针对斑秃的细胞因子靶向生物制剂疗法：作用机制、临床疗效及不良反应的全面综述
https://www.mdpi.com/2673-8449/5/2/11
Gaumond, S.I.; Kamholtz, I.; Jimenez, J.J. Cytokine-Targeting Biologic Therapies for Alopecia Areata: A Comprehensive Review of Mechanism of Action, Clinical Efficacy, and Adverse Events.Biologics2025,5, 11.
7. Analysis of Polyphenolic Composition, Antioxidant Power and Stress-Response Effects of Fractionated Perilla Leaf Extract on Cells In Vitro
紫苏叶分级提取物的多酚成分分析、抗氧化能力及体外细胞应激反应效应研究
https://www.mdpi.com/2673-8449/5/1/2
Lia, F.; Baron, B. Analysis of Polyphenolic Composition, Antioxidant Power and Stress-Response Effects of Fractionated Perilla Leaf Extract on Cells In Vitro.Biologics2025,5, 2.
8. Advancements in Pharmaceutical Lyophilization: Integrating QbD, AI, and Novel Formulation Strategies for Next-Generation Biopharmaceuticals
制药冻干技术的进步：融合质量源于设计（QbD）、人工智能（AI）与新型制剂策略，推动下一代生物制药的发展
https://www.mdpi.com/2673-8449/5/4/35
Atre, P.; Rizvi, S.A.A. Advancements in Pharmaceutical Lyophilization: Integrating QbD, AI, and Novel Formulation Strategies for Next-Generation Biopharmaceuticals.Biologics2025,5, 35.
9. Immune Response to Extracellular Matrix Bioscaffolds: A Comprehensive Review
细胞外基质生物支架免疫应答机制的全面综述
https://www.mdpi.com/2673-8449/5/3/28
Romero, D.J.; Hussey, G.; Capella-Monsonís, H. Immune Response to Extracellular Matrix Bioscaffolds: A Comprehensive Review.Biologics2025,5, 28.
10. Mesenchymal Stem Cells and Their Derivatives: Old Problems and New Possibilities in Regenerative Medicine for Neurological Diseases
间充质干细胞及其衍生物：神经系统疾病再生医学中的既有难题与新机遇https://www.mdpi.com/2673-8449/5/4/37
Akhmetzyanova, E.; Shulman, I.; Fakhrutdinova, T.; Rizvanov, A.; Mukhamedshina, Y. Mesenchymal Stem Cells and Their Derivatives: Old Problems and New Possibilities in Regenerative Medicine for Neurological Diseases.Biologics2025,5, 37.
期刊介绍
主编：Prof. Dr. Gary McLean
Biologics(ISSN 2673-8449) 是一个国际型开放获取英文学术期刊，旨在发表新兴和成熟生物制剂领域的研究成果, 为相关领域的学者提供一个学术交流的平台。目前期刊开设疫苗、诊断相关生物制剂、血液制品、单克隆抗体、细胞因子及相关介质、激素、蛋白质疗法、天然产物8个栏目。期刊目前已被Scopus, EBSCO, DOAJ等多个数据库收录.
2025 CiteScore：3.7
Time to First Decision：32.7 Days
Acceptance to Publication：4.7 Days
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